These final results, along with a previous report demonstrating that a small-molecule ACKR3 agonist CCX771 displays anxiolytic-like habits in mice,two support the notion of targeting ACKR3 as a singular way to modulate the opioid program, which could open new therapeutic avenues for opioid-linked Ailments.Tabernaemontana divaricata Conolidine is de